Abstract
Objective. Investigate the expression of TKs4 and MT1-MMP in oral squamous cell carcinoma (OSCC) and to relate it to clinicopathological data. Study Design. Fifty cases of OSCC and 20 cases of oral mucosa (OM) were subjected to immunohistochemical testing for the detection of TKs4 and metalloproteinase-(MMP). The expression of these proteins was evaluated in comparison to the normal tissue and between the different levels of clinical stage and histologic grade. Results. TKs4 and MT1-MMP were significantly expressed in OSCC compared to the OM (P
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