Abstract

THE AUTHORS COMPARED THE EXPRESSION OF THE P63 gene, a marker of epithelial stem cells, in normal conjunctiva and pterygium specimens. Immunostaining for p63 expression was performed on 10 matched pairs of pterygium and normal superior bulbar conjunctiva from the site of conjunctival graft harvesting. Immunopositivity reactions were seen in all samples. Levels of p63-positive cells were not statistically different between pterygium and normal conjunctiva (P = 0.7). The authors conclude that their results strongly support previous studies that pterygium arises as a result of incorrect control of cellular apoptosis rather than from an increase in proliferative capacity.—Michael D. Wagoner

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