Abstract

Objective To study expressions of p33ING1 proteins in extranodal nasal type NK/T cell lymphoma(ENKL). Methods p33ING1 were detected by immunohistochemistry in 37 cases of ENKL and 37 cases of benign lymphoid tissue proliferation. Results Expressions of p33ING1 and in ENKL were 67.57%, lower than that in benign lymphoid tissue proliferation. Low expression of p33ING1 in ENKL was correlation to patients' high level LDH. Conclusions Low or lost expression of p33ING1 may play on important role on the development and progression of ENKL. Key words: ENKL; p33ING1 ; Clinicopathological features

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