Abstract
Onychomycosis, a fungal infection of the nail, is predominantly caused by dermatophytes1. Our understanding of the pathogenic response to these fungi and their ability to establish chronic infection and evade immune clearance remains limited2. Evidence suggests an association between onychomycosis and immunosuppression3 but the nail plate represents a site of infection with negligible adaptive immune cell presence; the host response here led largely by components of the innate immune system4 including antimicrobial peptides (AMP). AMP are a cornerstone of innate host defence4, but their role in onychomycosis, is poorly understood. This study is the first detailed investigation of associations between innate immune defence gene expression and onychomycosis. This article is protected by copyright. All rights reserved.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
