Abstract
Expression of Concern: Adenoviral Gene Transfer of PLD1-D4 Enhances Insulin Sensitivity in Mice by Disrupting Phospholipase D1 Interaction with PED/PEA-15
Highlights
The bands in lanes one and two in the PKCzeta panel in Fig 4B appear similar to the bands in lanes three and four in the PKCzeta panel and to the bands in lanes three and four in the Tubulin panel with different aspect ratios
The underlying data confirmed that image fragments were spliced together in preparing Fig 3C but that the fragments originated from the same autoradiograph
The replication data supported the results shown in the figure
Summary
After this article [1] was published, concerns were raised about western blots in Figs 3C and 4B. The bands in lanes one and two in the PKCzeta panel in Fig 4B appear similar to the bands in lanes three and four in the PKCzeta panel and to the bands in lanes three and four in the Tubulin panel with different aspect ratios
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