Abstract
Merkel cell carcinoma (MCC) is an aggressive tumour of neuroendocrine origin. It has been shown that approximately 80% of MCC harbour a polyoma virus named Merkel cell polyoma virus (MCPyV).Activation-induced cytidine deaminase (AID), a member of the cytidine deaminase family, is essential for somatic hypermutation and class-switch recombination in immunoglobulin genes [1]. Recently, several lines of evidence have shown that inappropriately expressed AID induced by infections acts as a genomic mutator [...]
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