Abstract

ObjectiveTo explore the expression of Annexin II and its relationship with the cell differentiation, proliferation in lung cancer. MethodsRT-PCR and Western blot assays were used to detect the expression of Annexin II in lung cancer tissues and cell lines. ResultsAnnexin II was significantly up-regulated in lung cancer tissues, and in lung cancer cell lines, Annexin II had higher mRNA and protein expressions. ConclusionsAnnexin II is up-regulated in lung cancer, suggesting that the Annexin II has a potential value in the human lung cancer.

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