Abstract

Objective To study the expression and significance of Smac and XIAP in renal cell carcinoma(RCC). Methods The expressions of Smac and XIAP were detected using SP immunohistochemical technique in 95 cases of RCC and 10 cases of normal renal tissue. Results The postitive expressions of Smac were statistically significant differences in different clinical statges. The postitive expressions of XIAP were higher in RCC related to the lower histological grade. Smac protein and XIAP protein expression had negative correlation. Conclusions It indicate that Smac and XIAP may play an important role in RCC. The expression of Smac and XIAP are statistically significant associated with tumor grade and clinical stage. Key words: Renal cell carcinoma ; Smac ; XIAP ; Immunohistochemistry ;

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.