Abstract

Objective To study the expression and clinical significance of ezrin in breast carcinoma. Methods Immunohistuchemieal staining(S-P) was used to detect the expression of ezrin in 63 cases of breast car-cinoma samples. Results Among these 63 samples,the total expression rates of ezrin were 55.56% (35/63). With the increasing of axillary lymph nodes metastasis and clinical staging,the rates of expressing of ezrin elevated (P 5 years,or those whose DFS≤5 years or died within five years(P 0.05). Conclusion The expression of ezrin may contribute to prognostic e-valuation for breast carcinoma. Key words: Ezrin; Breast carcinoma; Immunohistochemistry; Prognosis

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