Abstract
Objective: Tumor-associated macrophages (TAMs) are associated with poor outcomes in ovarian cancer because of their immunosuppressive, protumor, and proangiogenic factors. This subset of macrophages is thought to express folate receptor beta (FRβ); therefore, we analyzed patient ascites samples for expression of FRβ and the ability of an anti-FRβ antibody (m909) to mediate antibody-dependent cellular cytotoxicity (ADCC).
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