Abstract
INTRODUCTION:This study aimed to investigate human exposure to Leishmania spp. infection and sandflies in an area endemic for the disease.METHODS:The presence of antibodies specific for Leishmania spp. and saliva of Lutzomyia spp. and that of L. infantum DNA in blood were evaluated.RESULTS: Antibodies against Leishmania spp. and sandfly saliva were observed in 20.8% and 37.7% of individuals, respectively. DNA of Leishmania spp. was amplified from the blood of one patient.CONCLUSIONS:The results suggest that Leishmania spp. infection may be underdiagnosed in this area.
Highlights
This study aimed to investigate human exposure to Leishmania spp. infection and sandflies in an area endemic for the disease
Due to the territorial expansion of human visceral leishmaniasis (VL) in Brazil and because the disease may be underdiagnosed in individuals living in endemic areas, the present study aimed to investigate exposure to Leishmania spp. infection and sandflies in individuals who were referred to a hospital located in an area endemic for the disease
DNA was amplified from the blood sample in only one patient (0.35%), a man with nonVL-compatible clinical signs, whose serologies were negative for both Leishmania spp. and sandfly saliva
Summary
This study aimed to investigate human exposure to Leishmania spp. infection and sandflies in an area endemic for the disease. DNA was amplified from the blood sample in only one patient (0.35%), a man with nonVL-compatible clinical signs, whose serologies were negative for both Leishmania spp. and sandfly saliva.
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