Abstract

EUROPEAN JOURNAL OF PSYCHO- TRAUMATOLOGY Supplement 1, 2012 Effects of Traumatic Stress Molecular and Hormonal Mechanism Abstracts from 42 nd Annual Conference New York, September 11–14, 2012

Highlights

  • Title Exposure to childhood trauma among pregnant women is associated with increased placental CRH production over gestation

  • A few studies that have examined the course and outcome of later pregnancies in women with early trauma history bring up the intriguing possibility of transgenerational transmission of the effect of maternal childhood trauma on her developing fetus

  • We address the hypothesis that history of early life trauma is associated with variation in the level and trajectory of placental corticotropin-releasing hormone (pCRH) production over the course of human gestation

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Summary

Introduction

Life stress restructures the nervous system. In rodents, the level of maternal care causes lifelong differences in central glucocorticoid (GC) sensitivity and memory. Title Exposure to childhood trauma among pregnant women is associated with increased placental CRH production over gestation Effects of Traumatic Stress Molecular and Hormonal Mechanism Abstracts from 42nd Annual Conference New York, September 11–14, 2012

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Conclusion

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