Abstract

It is too early to provide a clear answer on the impact of exposure to the second-hand aerosol of heated tobacco products (HTPs) in the planning of policy for smoke-free indoors legislation. Here, we conducted a preliminary study to evaluate indoor air quality with the use of HTPs. We first measured the concentration of nicotine and particulate matter (PM2.5) in the air following 50 puffs in the use of HTPs or cigarettes in a small shower cubicle. We then measured these concentrations in comparison with the use equivalent of smoking 5.4 cigarettes per hour in a 25 m3 room, as a typical indoor environment test condition. In the shower cubicle test, nicotine concentrations in indoor air using three types of HTP, namely IQOS, glo, and ploomTECH, were 25.9–257 μg/m3. These values all exceed the upper bound of the range of tolerable concentration without health concerns, namely 3 µg/m3. In particular, the indoor PM2.5 concentration of about 300 to 500 μg/m3 using IQOS or glo in the shower cubicle is hazardous. In the 25 m3 room test, in contrast, nicotine concentrations in indoor air with the three types of HTP did not exceed 3 μg/m3. PM2.5 concentrations were below the standard value of 15 μg/m3 per year for IQOS and ploomTECH, but were slightly high for glo, with some measurements exceeding 100 μg/m3. These results do not negate the inclusion of HTPs within a regulatory framework for indoor tolerable use from exposure to HTP aerosol, unlike cigarette smoke.

Highlights

  • Heated tobacco products (HTPs) are tobacco products that produce aerosols containing nicotine and other chemicals which are inhaled by users through the mouth [1]

  • Since the evidence available to date does not convincingly demonstrate that the available HTPs will replace conventional cigarettes among current smokers without attracting youths, or even that these products will substantially reduce health risks among users [2,9,10], it is regrettably too early to provide a clear answer on the long-term impact of exposure to the second-hand aerosol of heated tobacco products (HTPs) [1,5,7,8]

  • The no-observable-adverse-effect level (NOAEL) for nicotine was set at 0.5 mg/m3, based on a two-year rat inhalation study

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Summary

Introduction

Heated tobacco products (HTPs) are tobacco products that produce aerosols containing nicotine and other chemicals which are inhaled by users through the mouth [1]. In order to produce the nicotine-infused vapor, HTPs heat tobacco up to 350 ◦ C (lower than the 700 ◦ C reached with conventional cigarettes) using battery-powered heating systems [2]. Different HTP devices use different heating sources, including electronic energy via battery. HTPs have been marketed and promoted by the major tobacco companies as safer alternatives to combustible cigarettes [4]. The use of heated tobacco products (HTPs) has increased rapidly over the last few years in Japan [5]. In 2018, the overall prevalence of monthly HTP use was

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