Abstract
Exposure and Dose: Health Effect Studies Associated with Nanometer Aerosols
Highlights
The nanotechnology industry is rapidly growing with promises of substantial benefits that will have significant global economic and scientific impacts applicable to a whole host of areas from engineering and electronics to environmental remediation and medical healthcare
For 218Po, λA = 3.788*10-3 s-1 S = 8.84*10-7 [(1/f)-1] (1+7*104r) nm2/cm3; Figure 6 suggests that for the same concentration of the unattached activity fraction, the surface area of the particles will not depend on particle size for particles smaller than 100 nm (Ruzer, Apte, 2005)
Practical measurements of polydispersed and nonspherical particles in the nanometer range will need to be presented in the units of “equivalent surface area”, i.e., the surface area of monodispersed particles, which correspond to the same concentration of the unattached fraction
Summary
The nanotechnology industry is rapidly growing with promises of substantial benefits that will have significant global economic and scientific impacts applicable to a whole host of areas from engineering and electronics to environmental remediation and medical healthcare. Available quantitative data related to dosimetry of nanomaterials, and aerosoloized nanoparticles are very difficult to find. As it discussed in in terms of nanoparticles [2] we still don’t know: nature and extent of hazard; nature and extent of exposure; nature and extent of risk; What measure to use; limitation of controls; limitations of protection; What limits are appropriate? Despite the hundreds of products containing nanomaterials that are already being manufactured commercially, and the emerging body of scientific literature demonstrating the serious risk associated with nanotoxicity, there are still no laws to manage workplace exposure and to ensure workers’ safety. The measurement or assessment of the dose in practice, present substantial difficulties, and as a surrogate of the dose the term Exposure is used
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