Abstract
Bone represents the third most common site of metastatic spread [1] with potential severe effects including pain, fractures, immobility and decrease in quality of life [2]. Many patients suffering from symptomatic bone metastases experience relief from palliative external beam radiation therapy (pRT). Traditionally, pRT can consist of multi-fractionated radiation therapy (MFRT) schedules (such as 30 Gy in 10 fractions, 24 Gy in 6 fractions, 20 Gy in 5 fractions) or single fraction radiation therapy (SFRT) (such as 8 Gy in 1 fraction) [2]. More recently, high-dose stereotactic techniques have also been investigated [3,4].
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