Exploring the transition from injectable to non-injectable antibiotic administration - A prospective study

Abstract

Antibiotics are crucial in treating bacterial infections, and the mode of administration significantly influences patient adherence and outcomes. This prospective study aims to investigate the transition from injectable to non-injectable antibiotic administration, exploring the feasibility, patient acceptance, and clinical outcomes associated with this shift in a diverse patient population. The study employs a prospective observational design, enrolling patients across various healthcare settings. Patients initially prescribed injectable antibiotics for bacterial infections will be systematically transitioned to non-injectable formulations based on clinical criteria and feasibility assessments. Data collection includes patient demographics, clinical characteristics, reasons for the initial prescription of injectable antibiotics, and the rationale for transitioning to non-injectable alternatives. Adherence rates, patient satisfaction, and clinical outcomes, such as resolution of infection and adverse events, will be meticulously recorded. The primary outcomes of this study include the identification of factors influencing the transition from injectable to non-injectable antibiotics, patient acceptance of non-injectable formulations, and the impact on clinical outcomes. Subgroup analyses will be conducted to evaluate the feasibility of this transition in various patient populations, considering factors such as age, comorbidities, and the nature of the infection.