Abstract
ObjectivesIn this study, extracts from eight Pleurotus mushroom species were examined for their antioxidant properties. MethodsThe pure cultures of eight Pleurotus were grown, harvested, air-dried, pulverized, and for various biological activities. ResultsThe methanolic extract of Pleurotus florida showed the highest concentrations of total phenolics, total tannins, and flavonoids. It also displayed the greatest antioxidant activity in the FRAP, ABTS, metal chelating, superoxide anion radicals, hydrogen peroxide, nitric oxide and DPPH assay. In the hydroxyl radical scavenging assay, Pleurotus florida and Pleurotus flabellatus showed notable effects in methanolic and acetone extracts, respectively. Moreover, Pleurotus florida demonstrated a strong antioxidant effect on β-carotene in methanolic extracts. The study also explored the potential of mushrooms as natural anti-diabetic treatments by targeting a key enzyme in biopharmaceuticals. Pleurotus florida's methanolic extract at a concentration of 1000 µg/ml exhibited significant α-amylase inhibition (99.02%), surpassing acarbose's efficiency at the same concentration (96.54%). ConclusionOverall, the bioactive components from Pleurotus florida showed effective antioxidant and antidiabetic effects under in vitro conditions.
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