Abstract

This review explains the therapeutic prospective of Azadirachta indica (Neem), a traditional medicinal tree in India, Southeast Asia, and Africa. Neem extracts have been found to have various therapeutic properties, including antimicrobial, antifungal, hepatoprotective, antiulcer, antifertility, and antinociceptive properties. Recent research has shown neem’s potential as an antiviral agent, cancer treatment, and a source of antibiotic compounds. Neem oil nano hydrogel shows significant antimicrobial activity against various pathogens. The plant also has the potential to mitigate heavy metal pollution and develop a model for predicting soil remediation using neem leaves. Neem’s inhibitory activity on papain-like protease of SARS-CoV-2 is also explored. Overall, neem’s therapeutic potential is significant and its potential in healthcare and environmental remediation is highlighted.

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