Abstract
Background: Long-term survival in acute coronary syndrome has increased steadily in the last decades. Follow-up studies developed in this patient clearly reveal that they are at risk of suffering a new event, placing them in a new stage, secondary prevention. Assuming this increased risk, the control target of their cardiovascular risk factors become more ambitious. In this field, control of Cholesterol levels, particularly LDL-C, has arisen as a priority objective in patients with coronary arterial disease. In this sense, management of dyslipidemia guidelines, recently recognises the role of functional food, highlighting among them is the Red Yeast Rice (RYR). The aim of the study is to establish the potential role of functional food, in secondary prevention, while determining its additional capacity to reduce LDL-C in patients that despite optimal classic treatment (maximum tolerated dose of stain plus Ezetimibe) is still out of control objectives. Results and Discussion: 88 patients were included and after 3 months of treatment with RYR, their lipid profiles were compared with the baseline. The variation of T-Col, LDL-C and Trig were statistically significant. A reduction in LDL-C was 10.73 mg/dL, which means a 10.93% of additional reduction over the standard therapy the patients were receiving. Concerning security, no relevant side effects were reported when adding RYR, even in a relevant percentage (35.4%), myalgia disappeared (especially when reducing the titrating dose of the statin). Conclusion: Adding RYR in secondary prevention patients in combination with the usual treatment, seems to be an effective alternative to optimize LDL levels and thus gets closer to the target set in the guidelines, without adding relevant side effects, and even improving tolerance to the statins.
Highlights
The survival rate of the acute coronary syndrome has increased in a relevant and sustained way over recent decades
Follow-up studies developed in this patient clearly reveal that they are at risk of suffering a new event, placing them in a new stage, secondary prevention
Adding Red Yeast Rice (RYR) in secondary prevention patients in combination with the usual treatment, seems to be an effective alternative to optimize LDL levels and gets closer to the target set in the guidelines, without adding relevant side effects, and even improving tolerance
Summary
The survival rate of the acute coronary syndrome has increased in a relevant and sustained way over recent decades. Follow-up studies of these patients clearly reveal that they are at risk of suffering another event, placing them in a new stage, secondary prevention Assuming this increased risk, cardiovascular risk factor control targets become more ambitious. Follow-up studies developed in this patient clearly reveal that they are at risk of suffering a new event, placing them in a new stage, secondary prevention Assuming this increased risk, the control target of their cardiovascular risk factors become more ambitious. The control target of their cardiovascular risk factors become more ambitious In this field, control of Cholesterol levels, LDL-C, has arisen as a priority objective in patients with coronary arterial disease. Conclusion: Adding RYR in secondary prevention patients in combination with the usual treatment, seems to be an effective alternative to optimize LDL levels and gets closer to the target set in the guidelines, without adding relevant side effects, and even improving tolerance
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.