Abstract
[(17α,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester], widely known under the name of YK11 is a synthetic agent with anabolic properties which belongs to the selective androgen receptor modulators group (SARMs). An extended polymorph screening was accomplished and the crystal structures of three YK11 polymorphs were determined by single crystal X-ray diffraction. The crystal features were analyzed by means of crystal lattice and intermolecular interaction energies as well. Furthermore, the polymorphs were investigated by powder X-ray diffraction, Fourier-Transform infrared spectroscopy and DSC thermal analysis.
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