Abstract

The aim of the study is to explore the impact of ketamine on sound perception and spatial orientation decision making, and the mechanism of how ketamine impacts perception and decision abilities. The methods used include behavioral and histology approaches. From the results, it can be concluded one of the brain regions affected by ketamine is TeA(temporal association area), which plays a vital role in sound perception and spatial orientation. An unexpected finding is that ketamine impacts left turning and right turning decisions at different degree, which requires further research on ketamine’s different impact on two cerebral hemispheres. In all, the study’s findings help people further understand how ketamine impacts spatial and sound perception.

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