Abstract
As a chemotherapeutic agent heavily used since the 1970s, Doxorubicin's (DOX) mission is well known and carried out, to halt cancerous cell replication and cause cancerous cells to die. DOX accomplishes this by binding to DNA and inhibiting topoisomerase II during the replication of a cell causing cellular apoptosis. The necessary concentration for this to happen and the way in which these interactions are carried out at the molecular level is still under debate. We use dual-beam optical tweezers to trap and isolate a single DNA molecule.
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