Abstract

BackgroundPrevious studies have shown an association between experience of intimate partner violence and abuse (IPVA) and depression. Whether this is a causal relationship or explained by prior vulnerability that influences the risk of both IPVA and depression is not known.MethodsWe analysed data from the Avon Longitudinal Study of Parents and Children prospective cohort (N = 1764 women, 1028 men). To assess the causal association between IPVA at 18–21 years old and logged depressive symptom scores at age 23, we used (i) multivariable linear regression, (ii) inverse probability of treatment weighting (IPTW), and (iii) difference-in-difference (DiD) analysis, which compared the mean change in logged depressive symptom scores between ages 16 and 23 between those who experienced IPVA and those who did not.ResultsWomen who experienced IPVA had on average 26% higher depressive symptom scores after adjustment for measured confounders (ratio of geometric means 1.26, 95% CI 1.13 to 1.40). In men, the difference was 5% (ratio of geometric means 1.05, 95% CI 0.92 to 1.21). Results from IPTW analysis were similar. In the DiD analysis, there was no evidence that being exposed to IPVA affected the change in depressive symptom scores over time compared to being in the non-exposed group for either women (difference-in-differences 1%, −12 to 16%) or men (−1%, −19 to 20%).ConclusionsMultivariable linear regression and IPTW suggested an association between IPVA and higher depressive symptom score in women but not men, but DiD analysis indicated a null effect in both women and men. This suggests the causal origins of higher depressive symptoms in this young adult population are likely to reflect prior vulnerability that leads to both higher depressive symptoms and increased risk of IPVA exposure.

Highlights

  • Previous studies have shown an association between experience of intimate partner violence and abuse (IPVA) and depression

  • Cohort characteristics Of 1764 women and 1028 men in the study cohort, 482 (27%) and 210 (20%) reported that they had been victimised between ages 18 and 21, respectively; characteristics of participants according to whether or not they experienced IPVA victimisation are presented in Additional file 1: Table S1 [20, 21, 30,31,32, 34, 45]

  • inverse probability of treatment weighting (IPTW) When regression estimates were inverse probability of treatment weighted, associations between IPVA and depressive symptoms were in line with the multivariableadjusted results

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Summary

Introduction

Previous studies have shown an association between experience of intimate partner violence and abuse (IPVA) and depression Whether this is a causal relationship or explained by prior vulnerability that influences the risk of both IPVA and depression is not known. Longitudinal studies investigating the relationship between IPVA and depression consistently report bidirectional associations, they usually do not have strong study designs and robust analytical approaches for assessing causality [4]. Confounding may influence these findings if background factors such as adversity in childhood influence both the risks of experiencing IPVA and depressive symptoms. If associations are not causal, whilst prevention of IPVA and support to survivors is still essential, we need effective interventions in earlier stages of the life course to prevent adult mental health problems

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