Abstract
This is the first of two papers. The first paper outlines the literature review that informed the pilot study; the second describes the qualitative pilot study: stress, immunity and preterm birth pilot study (SIPP). The review examined qualitative research to understand the area of investigation and determine whether this corresponded with the findings of the pilot study. The SIPP study used semi-structured interviews exploring women's answers to a life events questionnaire as part of a larger quantitative prospective observational study, the stress, immunity and preterm birth (SIP) study. The SIP study examined the association between maternal stress, maternal immune response and pregnancy outcome in women with a history of recurrent idiopathic preterm labour. The review evolved into three broad themes: the impact of perinatal loss on a subsequent pregnancy; the preterm labour experience; and disenfranchised grief.
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