Abstract
The Ocean, which is called the “mother of origin of life,” is also the source of structurally unique natural products that are mainly accumulated in living organisms. Cyanobacteria are photosynthetic prokaryotes used as food by humans. They are excellent source of vitamins and proteins vital for life. Several of these compounds show pharmacological activities and are helpful for the invention and discovery of bioactive compounds, primarily for deadly diseases like cancer, acquired immunodeficiency syndrome (AIDS), arthritis, and so forth, while other compounds have been developed as analgesics or to treat inflammation, and so forth. They produce a large variety of bioactive compounds, including substances with anticancer and antiviral activity, UV protectants, specific inhibitors of enzymes, and potent hepatotoxins and neurotoxins. Many cyanobacteria produce compounds with potent biological activities. This paper aims to showcase the structural diversity of marine cyanobacterial secondary metabolites with a comprehensive coverage of alkaloids and other applications of cyanobacteria.
Highlights
They are excellent source of vitamins and proteins vital for life. Several of these compounds show pharmacological activities and are helpful for the invention and discovery of bioactive compounds, primarily for deadly diseases like cancer, acquired immunodeficiency syndrome (AIDS), arthritis, and so forth, while other compounds have been developed as analgesics or to treat inflammation, and so forth
This paper aims to showcase the structural diversity of marine cyanobacterial secondary metabolites with a comprehensive coverage of alkaloids and other applications of cyanobacteria
Cyanobacteria is a phylum of bacteria that obtain their energy through photosynthesis
Summary
Cyanobacteria is a phylum of bacteria that obtain their energy through photosynthesis. The drug is used in the treatment of Hodgkin’s lymphoma, squamous cell carcinomas, and testicular cancer, as well as in the treatment of plantar warts and as a means of effecting pleurodesis The discovery of these unique classes of natural products from marine cyanobacteria represents an important source of novel microbial secondary metabolites, in addition to the actinomycetes and fungi, for drug discovery efforts. An increasing number of marine cyanobacterial compounds are found to target tubulin or actin filaments in eukaryotic cells, making them an attractive source of natural products as anticancer agents [8] Prominent molecules such as the antimicrotubule agents, curacin A (Figure 3) and dolastatin 10 (Figure 2), have been in preclinical and/or clinical trials as potential anticancer drugs [9]. Efforts are underway to commercialize algae-based fuels such as diesel, gasoline, and jet fuel [19,20,21,22,23,24]
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