Exploring Forensic Challenges and Insights: Implications of Genetic Analyses on Degraded DNA Samples

Abstract

Identifying missing persons from different types of body parts poses an intricate challenge for law enforcement and forensic experts. Identification through human remains is challenging when the available body parts don't contain distinctive features, commonly used for anthropological analysis. The complexities arise from the fragmentation of remains and difficulties in obtaining viable biological samples due to decomposition and expose to other factors enhancing degradation. The absence of personal information and known reference samples for familial identification further amplifies the complexities in the process. When dealing with different types of human remains and lacking additional information of those missing individuals, the analysis centered on DNA as the most dependable and potentially definitive method for identification. In such scenario, it is imperative to select ideal tissue among different tissue types for DNA extraction followed by optimized DNA extraction protocols and STR amplification kits with different markers to achieve consistent DNA profiling in identification purposes.