Exploring drug discovery and development strategies in the context of monkeypox: A comprehensive investigation

Abstract

Monkeypox is a rare but potentially serious viral infection that has re-emerged as a major public health problem due to recent outbreaks and the increased likelihood of zoonotic transmission. This review delves into the dynamic landscape of monkeypox drug discovery and drug development, revealing the multifaceted challenges and remarkable progress in the fight against this evolving infectious disease. This summary provides a comprehensive overview of ongoing efforts to identify effective antivirals, explore the potential for repurposing medicines, and pioneer innovative therapeutic strategies. As the search for effective treatments gains momentum, the abstract highlights the critical role of collaborative research efforts, the integration of cutting-edge technologies, and the need to adopt a multidisciplinary approach to address monkeypox complexity. In addition, the abstract highlights the critical importance of assessing the current status and future prospects of monkeypox drug development. By analysing the many factors shaping the field, including viral pathogenesis, host immune responses, and viral genetic diversity, this review contributes to a comprehensive understanding of the challenges inherent in addressing monkeypox.