Abstract
In response to the challenge posed by antimicrobial resistance and the demand for innovative anticancer drugs, the aim of this study was to examine the potential source of natural antioxidant, antimicrobial, and anticancer compounds from purple flowers of Bougainvillea glabra. The dried purple flower of B. glabra was sequentially extracted with hexane, ethyl acetate, methanol, and water. The extracts were used for investigating antioxidants, antimicrobial activity, anticancer properties, and phytochemical composition. The methanol extraction exhibited the highest total phenolic content and in vitro antioxidant activity. The hexane and ethyl acetate extracts exhibited antimicrobial activity against a broad range of microorganisms in both American type of culture collection (ATCC) and clinical strains, while the methanol extract displayed a narrower antimicrobial profile that implied the promise of B. glabra as a developmental reservoir of specific antimicrobial agents. Notably, the hexane extract demonstrated the most promising anticancer activity against various cancer cell lines, including lung cancer (A549), colon cancer (HT-29), breast cancer (MCF-7), and bile duct cancer (KKU-213A). In conclusion, this study reveals the pharmaceutical potential of crude extracts from B. glabra flowers; thereby, paving the way for future exploration of these compounds within the drug development industry.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
