Abstract

BackgroundSingapore’s healthcare system presents an ideal context to learn from diverse public and private operational models and funding systems.AimTo explore processes underpinning decision-making for antibiotic prescribing, by considering doctors’ experiences in different primary care settings.MethodsThirty semi-structured interviews were conducted with 17 doctors working in publicly funded primary care clinics (polyclinics) and 13 general practitioners (GP) working in private practices (solo, small and large). Data were analysed using applied thematic analysis following realist principles, synthesised into a theoretical model, informing solutions to appropriate antibiotic prescribing.ResultsGiven Singapore’s lack of national guidelines for antibiotic prescribing in primary care, practices are currently non-standardised. Themes contributing to optimal prescribing related first and foremost to personal valuing of reduction in antimicrobial resistance (AMR) which was enabled further by organisational culture creating and sustaining such values, and if patients were convinced of these too. Building trusting patient-doctor relationships, supported by reasonable patient loads among other factors were consistently observed to allow shared decision-making enabling optimal prescribing. Transparency and applying data to inform practice was a minority theme, nevertheless underpinning all levels of optimal care delivery. These themes are synthesised into the VALUE model proposed for guiding interventions to improve antibiotic prescribing practices.These should aim to reinforce intrapersonal Values consistent with prioritising AMR reduction, and Aligning organisational culture to these by leveraging standardised guidelines and interpersonal intervention tools. Such interventions should account for the wider systemic constraints experienced in publicly funded high patient turnover institutions, or private clinics with transactional models of care. Thus, ultimately a focus on Liaison between patient and doctor is crucial. For instance, building in adequate consultation time and props as discussion aids, or quick turnover communication tools in time-constrained settings. Message consistency will ultimately improve trust, helping to enable shared decision-making. Lastly, Use of monitoring data to track and Evaluate antibiotic prescribing using meaningful indicators, that account for the role of shared decision-making can also be leveraged for change.ConclusionsThese VALUE dimensions are recommended as potentially transferable to diverse contexts, and the model as implementation tool to be tested empirically and updated accordingly.

Highlights

  • Antimicrobial resistance (AMR) is a rising global health threat

  • Antibiotic stewardship guidelines have primarily focused on tertiary hospitals, while such recommendations remain lacking in outpatient settings [2,3,4]

  • In 2016, the US Centers for Disease Control and Prevention (CDC) released a guiding framework for antibiotic stewardship in outpatient settings, which included primary care clinics, to extend monitoring and improvement of antibiotics use in such contexts [5]

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Summary

Introduction

Antimicrobial resistance (AMR) is a rising global health threat. It has been projected that 10 million annual deaths would be attributable to AMR by 2050, with nearly half of these occurring in Asia [1]. In 2016, the US Centers for Disease Control and Prevention (CDC) released a guiding framework for antibiotic stewardship in outpatient settings, which included primary care clinics, to extend monitoring and improvement of antibiotics use in such contexts [5]. Antibiotic prescribing itself has been described as an adaptive expertise, which requires the incorporation of clinical knowledge, experience and cognitive styles, but which is framed by the characteristics of the patient [6]. Prescribing decisions have been found to be made under varying levels of support, cognitive loading as well as consideration of patient expectations, demands and self-presentation [6]. On the primary care doctor’s side, antibiotic prescribing has been shown to be dependent on their presentation of ‘expert self ’, ‘benevolent self ’ and ‘practical self ’ during the clinical consultation [7]. Singapore’s healthcare system presents an ideal context to learn from diverse public and private opera‐ tional models and funding systems

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