Abstract
Antimicrobial drugs are those drugs which are used to treat diseases caused by microorganisms. To treat the diseases caused by pathogenic microorganisms antibiotic, antiviral, antifungal and antiparasitic medicines are used. These microbes produces diseases in humans, animals and plants. According to World Health Organization (WHO). The cases of Antimicrobial resistance (AMR) is increasing day by day and it threatens the effective treatment and prevention of infections caused by bacteria, viruses, fungi and parasites. AMR occurs when these microbes gets resistance against the effects of medications, which makes common infections difficult to treat and hence increases the risk of severe illness, disease spread and death. As a result, the medicines becomes ineffective, infections remains in the body and increases the probability of spread to others. WHO recommends that decreased use of synthetic antibiotics and increased use of herbal antimicrobial drugs are the only ways by which the AMR can be controlled or eliminated. Herbal drugs are considered to be effective and free from side effects. In the present article we discussed about Aegle Marmelos Linn. (Bael) which is useful in treating many health ailments. It possess many pharmacological activities like anticonvulsant, antioxidant, antihyperglycemic, anxiolytic, antidepressant, antihistaminic, antimicrobial, hepatoprotective, analgesic, immune modulatory, cardio protective and antithyroid activity. Due to its antibacterial activity it is used to treat many infections caused by bacteria and also have antiulcer activity due to which it is used to treat ulcer patients. The bacteria, Helicobacter pylori is one of the cause of peptic ulcer. This review article discusses about the effect of Aegle Marmelos on this bacteria. Keywords: Antibacterial, Antiulcer, Aegle marmelos, Helicobacter pylori, Peptic ulcer, Antimicrobial, Bael.
Highlights
The relation between peptic ulcer disease and H. pylori infection has been found over the last few decades and documented studies says that H. pylori infection causes 90% of duodenal ulcers and up to 70% of gastric ulcers
Isolated phytoconstituents responsible for antibacterial activity of leaves of Aegle marmelos. They tested it on four bacterias i.e. Staphylococcus aureus, Solmonella typhi, Bacillus subtilis and Escherichia coli which showed that it had a high efficiency of destroying bacteria. 26
World Health Organization (WHO) recommends the use of herbal drugs to reduce Antimicrobial resistance (AMR)
Summary
Pathogenic microorganisms causes infection and which leads to many diseases in human, animals and plants. To those diseases antimicrobial drugs are used like antibacterial, antifungal antiviral and antiparasitic drugs. Due to excessive use of the antimicrobial drugs, microbes are getting resistance towards these drugs which means that the medications are becoming ineffective. WHO says it’s a global problem and recommends to decrease the synthetic antimicrobial drugs and in place of that herbal antimicrobial. 1 These are the ways by which AMR can be controlled or eliminated Drugs should be used. 1 These are the ways by which AMR can be controlled or eliminated
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