EXPLORING ANALGESIC ACTIVITIES OF GANITRI LEAVES THROUGH ETHANOL AND METHANOL EXTRACTS

Abstract

This study delves into the analgesic potential of Ganitri leaves through the extraction and evaluation of ethanol and methanol extracts. The investigation aims to contribute valuable insights into the pharmacological properties of Ganitri, shedding light on its potential as a natural analgesic agent Ganitri (Genus: Ganitrus) is a plant with significant medicinal potential, and its leaves have been traditionally used in various folk remedies. This study explores the analgesic properties of ethanol and methanol extracts derived from Ganitri leaves. The objective of the research is to investigate the potential pain-relieving effects of these extracts through various experimental assays. The extraction process involves the use of ethanol and methanol solvents to obtain bioactive compounds from Ganitri leaves. The analgesic activities of the extracts are assessed using established animal models, including the hot plate test and acetic acid-induced writhing test. Additionally, the study evaluates the extracts for their anti-inflammatory effects. Preliminary findings indicate that both ethanol and methanol extracts exhibit significant analgesic activities, as evidenced by a decrease in response latency in the hot plate test and a reduction in the number of writhing episodes in the acetic acid-induced writhing test. The anti-inflammatory effects of the extracts further contribute to their potential as pain-relieving agents. Further investigations into the chemical composition of the extracts are conducted through phytochemical analysis, aiming to identify and characterize the bioactive compounds responsible for the observed analgesic effects. This study provides valuable insights into the pharmacological properties of Ganitri leaves and highlights their potential as a natural source for the development of analgesic agents. In conclusion, the ethanol and methanol extracts of Ganitri leaves demonstrate promising analgesic activities, suggesting their potential use in the management of pain-related conditions. Future research endeavors may focus on elucidating the mechanisms of action and conducting clinical trials to validate the safety and efficacy of these extracts as analgesic agents.