Abstract
Objective: To investigate the myocardial damage and hyperbaric oxygen treatment of acute encephalopathy in CO poisoning. Methods: Since March 2015 - March 2020 admitted to 125 patients with acute CO poisoning encephalopathy, emergency admission GCS score 7-8 points or less, and the intracranial pressure, myocardial damage markers enzymes (CK - MB, CK, LDH, MYO, BNP) and troponin (cTnl), arterial COHb quantitative and electrocardiogram (EKG) dynamic inspection, row CT, MRI examination can at the same time, using air pressure cabin HBO treatment, Each patient choose 2.5-3 period of treatment (Every10 times is a course of treatment), 99.5-100% oxygen purity (liquid oxygen gasification), oxygen supply time 60 minutes or 80 minutes, interlude 10 minutes. Results: The higher the COHb, the deeper the coma, the increased intracranial pressure, the intracranial hypertension, and the morphological changes such as diffuse cerebral edema and symmetrical globulin necrosis were observed in 125 patients. However, the myocardial damaging enzymes and troponin markers were significantly increased and the EKG abnormalities were basically consistent. HBO treatment achieved remarkable curative effect, the incidence of delayed encephalopathy was significantly reduced, and no death occurred. Conclusion: Increased intracranial pressure induced by acute encephalopathy induced by CO poisoning can significantly increase the incidence of myocardial damage, subendocardial myocardial infarction, left heart failure and various arrhythmias. HBO is a treatment for etiology and should be preferred.
Highlights
Acute carbon monoxide poisoning (ACMP) is a whole world problem
The carbon monxiide poisoning encephalopathy leads to increasd intracranial pressure and diffuse cerebral edema, resulting in severe damage of myocardium and its hear, leading to subendocardial myocardial infarction, acute heart failure, delayed encephalopathy and so on, which is the main cause of severe disability and death
From March 2010 to March 2020, a total of 551 cases of CO poisoning were admitted to our department, among which 125 cases of acute encephalopathy were treated with severe myocardial damage secondary to HBO treatment
Summary
Acute carbon monoxide poisoning (ACMP) is a whole world problem. The mortality rate is highest in posioning diseases. The carbon monxiide poisoning encephalopathy leads to increasd intracranial pressure and diffuse cerebral edema, resulting in severe damage of myocardium and its hear, leading to subendocardial myocardial infarction, acute heart failure, delayed encephalopathy and so on, which is the main cause of severe disability and death. Belong to critical disease secondary to acute CO poisoning encephalopathy is the most typical clinical anoxic encephalopathy in a type, mainly located in parenchymal damage and become a diffuse, appear vascular source sex brain edema, and cause of diffuse intracranial pressure or lead to increasing pressure in a coma, is in different parts and coronary artery myocardial damage is one of the reasons for the heavier. From March 2010 to March 2020, a total of 551 cases of CO poisoning were admitted to our department, among which 125 cases of acute encephalopathy were treated with severe myocardial damage secondary to HBO treatment. The report is as follows: Zhang Yanping et al.: Explore of Hyperbaric Oxygen Therapy on the Patients with Acute Encephalopathy
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