Exploration of Ultrasound‐Sensitive Biomaterials in Cancer Theranostics

Abstract

AbstractCancer is a serious health problem to be solved. With the development of biomaterials, enhanced diagnostic and controllable therapeutic strategies for cancer have emerged, revealing encouraging results with a promising future. Due to its outstanding tissue penetration and controllability, along with a series of bioeffects on tissues, ultrasound (US), as a common medical technology, has been regarded as an effective tool against cancer, and its use has promoted the exploration of US‐sensitive biomaterials. In this review, the bioeffects of US are first introduced and then the main US‐sensitive biomaterials (containing cavitation nuclei, sonosensitizers, and US‐responsive macromolecular systems) used to treat cancer, followed by a summary of several applications based on US‐sensitive biomaterials, from diagnosis to therapy. Finally, the emerging challenges in this field that need to be overcome are highlighted. This review reports the progress of US‐sensitive biomaterials, providing new possibilities in cancer theranostics and thus benefiting patients.