Exploration immunologique de l’œil

Abstract

AbstractThe immune system of the eye has special and specific characteristics. Indeed, this organ benefits from a special status called immune privilege which allows, via different mechanisms, to limit the immune inflammatory response in order to protect vision. Ocular pathologies are therefore often localized. In addition, the clinical manifestations of these pathologies could be non-specific, which makes their diagnosis difficult. The biological exploration of the immune system of the eye is therefore a valuable help in the diagnosis and monitoring of some of these pathologies: this article presents in particular the interest of interleukin (IL)-l0 assay and the IL-I0/IL-6 ratio in ocular samples for the diagnosis and monitoring of intraocular lymphoma, of pro-inflammatory cytokines for uveitis and of total IgE for allergic conjunctivitis.