Exploration and Study of Jianpi Qushi Powder Combined with Standard Anti HP Quadruple Therapy in the Treatment of HP Infectious Gastritis of Spleen Deficiency and Dampness Stagnation Type

Qiangcai Mai,Xiuling Wei,Xinrong Huang,Xiaoye Su,Min Yang,Lihua Qin,Miaoling Liang,Shoulan Gong,Yu Gan,Buqing Su,Guosheng Su

doi:10.4236/ns.2022.142006

Abstract

Objective: To explore the therapeutic effect of traditional Chinese medicine Jianpi Qushi powder combined with standard anti-HP quadruple therapy in the treatment of HP infectious gastritis with spleen deficiency and dampness stagnation. Methods: From January 2020 to December 2021, 223 patients with laboratory-confirmed HP infection who were admitted to the Outpatient and Inpatient Department of Internal Medicine in our hospital were selected as the research objects and randomly divided into two groups. 101 patients in the control group were given standard anti HP quadruple therapy; 122 cases in the treatment group were given traditional Chinese medicine Jianpi Qushi powder combined with standard anti HP quadruple therapy. The two groups were rechecked carbon breath test after the designed course of treatment, and the curative effects of the two groups were compared. Results: 113 cases in the treatment group were cured by traditional Chinese medicine Jianpi Qushi powder combined with standard anti HP quadruple therapy, and the cure rate was 92.62%. 84 cases in the control group were cured by standard anti HP quadruple therapy, and the cure rate was 83.17%, χ2 = 4.7955, P = 0.0285, the difference was statistically significant (P

Highlights

Since the discovery of Helicobacter pylori (HP), a large number of studies at home and abroad have shown that [1,2,3,4,5,6,7,8], Helicobacter pylori is the main cause of infection of chronic active gastritis and peptic ulcer; Helicobacter pylori infection is associated with gastric lymphoma, gastric cancer and dyspepsia
In order to understand the therapeutic effect of traditional Chinese medicine Jianpi Qushi powder on HP infectious gastritis of spleen deficiency and dampness stagnation type, this study used traditional Chinese medicine Jianpi Qushi powder combined with standard anti HP quadruple therapy to explore and study the treatment of HP infectious gastritis of spleen deficiency and dampness stagnation type
9 cases of Helicobacter pylori were still positive in 122 cases, accounting for 7.38%; the number of negative cases after treatment was compared with the number of still positive cases, χ2 = 177.3115, P = 0.0000, the difference was statistically significant

Summary

Introduction

Since the discovery of Helicobacter pylori (HP), a large number of studies at home and abroad have shown that [1,2,3,4,5,6,7,8], Helicobacter pylori is the main cause of infection of chronic active gastritis and peptic ulcer; Helicobacter pylori infection is associated with gastric lymphoma, gastric cancer and dyspepsia. The treatment of Helicobacter pylori infection is facing greater challenges [13,14,15,16]. The treatment plan of Helicobacter pylori has changed from tripartite combination to quadripartite combination, and the course of treatment has been extended continuously. The treatment of HP has entered a difficult period, and the exploration of traditional Chinese medicine for the treatment of HP infection has become a new idea for many domestic researchers [17, 18]. Some domestic scholars and research institutions have studied the treatment plan of traditional Chinese medicine, and made some breakthroughs with definite curative effect, which has been well received by the majority of patients [19].

Methods

Results

Discussion

Conclusion