Abstract
Systemic sclerosis (SSc) is an autoimmune disease characterized by systemic autoimmunity and tissue fibrosis of the skin and internal organs (Medsger, 2003). Early clinical interventions for SSc lead to early detection of complications, resulting in improved patient prognosis (Denton and Khanna, 2017). Therefore, early diagnosis of SSc is important. SSc presents with characteristic skin manifestations such as Raynaud’s phenomenon and skin sclerosis from early onset (Gunnarsson et al., 2016; LeRoy, 1992).
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