Abstract

Abstract Background and Aim: Hypoglycemia, marked by low blood glucose levels, presents significant challenges in diabetes care. This review outlines the evidence-based recommendations formulated by the DGENius Experts Consensus Group for managing hypoglycemia in people with diabetes. The goal was to furnish well-defined, evidence-based recommendations for addressing and comprehending hypoglycemia within diverse contexts, encompassing diabetes management, and various medical conditions. Materials and Methods: The consensus statement was crafted through an extensive literature review involving peer-reviewed articles, clinical guidelines, and relevant publications. A diverse panel of experts with broad knowledge and experience convened for structured deliberation, followed by multiple rounds of rigorous review and meetings to reach the final consensus statement. Results: The consensus introduces the importance of effective hypoglycemia in people with diabetes management, addressing both type 1 and type 2 diabetes mellitus separately, with tailored recommendations. It also covers impact of hypoglycemia on cardiovascular health and related recommendations. The document extends its scope to co-existing medical conditions, encompassing chronic renal dysfunction, hepatic and neoplastic disorders; hypoglycemia in specialized circumstances, such as during physical exertion, administration of oral antidiabetic agents, fasting periods, hospital-based care, reduced symptomatic awareness, nocturnal episodes, alcohol intake, pregnancy, and following metabolic surgical interventions; hypoglycemia in the context of nonantidiabetic medications; and hypoglycemia among the elderly. Quality of life and patient awareness are emphasized, and the statement concludes with prevention, treatment, and technology utilization recommendations. Conclusion: This comprehensive consensus statement is designed to guide healthcare professionals in managing hypoglycemia optimally. The goal is to heighten awareness of this critical condition, improve patient outcomes, and enhance their quality of life.

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