Abstract
The production of bronchial stenosis by the simple method of the endobronchial application of a caustic has given rise to considerable experimental work. Adams and Livingstone painted the orifice of a bronchus with a 35% silver nitrate solution, which resulted in complete stenosis of that bronchus in a high percentage of attempts. This demanded repetition in view of the many possibilities for the application of such a method in clinical conditions.Following the technique of Adams and Livingstone1 we have failed to produce complete stenosis in either dogs or monkeys in experiments during the last 1 1/2 years. Either we produced so great a destruction that rupture of the bronchus or a serious pneumonitis distal to the bronchus occurred, or stenosis failed to result. Stenosis with complete collapse of the lobe distal to this occurred in but a small percentage of our animals.The desirability of the method led to a search for other solutions which might be more efficacious. To produce a permanent bronchial occ...
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