Abstract
. The article is devoted to the experimental study of the effectiveness of AMIC technology in the surgical treatment of full-thickness defects in hyaline cartilage. Purpose of the study - study the biological potential of collagen membranes and their ability to transform into cartilage tissue. The study was conducted on 4 pigs. On the joints of the hind limbs, full-thickness cartilage defects and implantation of 2 different collagen membranes were formed. Animals were removed from the experiment in the period 2,3,4,6 months after surgery. The article presents a morphological analysis of the nature of cartilage tissue regeneration 6 months after surgery. The study showed the high biological potential of collagen membranes and their ability to transform into hyaline cartilage.
Highlights
За последнее десятилетие для восстановления хрящевых дефектов в клиническую практику стали широко внедряться разнообразные биотехнологии, в том числе и технология индуцированного матрицей аутохондрогенеза - AMIC [1,8,13,14]
The article is devoted to the experimental study of the effectiveness
Purpose of the study - study the biological potential of collagen membranes
Summary
За последнее десятилетие для восстановления хрящевых дефектов в клиническую практику стали широко внедряться разнообразные биотехнологии, в том числе и технология индуцированного матрицей аутохондрогенеза - AMIC (autologous matrix indused chondrogenesis) [1,8,13,14]. Мембрана Chondro-Gide является одним из самых востребованных биопродуктов для восстановления хрящевой ткани и широко используется в клинической практике. Метод формирования мембраны и ее структура (Рис.2б) радикально отличают ее от мембраны Chondro-Gide, что позволяет произвести объективный сравнительный анализ биологического потенциала обеих мембран и качество их трансформации в хрящевую ткань.
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