Abstract

N UMEROUS experments have been made on animals in order to clarify the question of the origin and absorption of amyloid. The results of these experiments seem to indicate that experimentally produced deposits of amyloid can be made to disappear. A few observations have been made on human beings, but only in the case of generalized amyloidosis has evidence been encountered for the definite disappearance of amyloid from certain sites. Waldenstrom, 1 in several biopsies of spleens and livers of 10 patients with generalized amyloidosis noted in all of them the gradual, occasionally complete disappearance of deposits of amyloid. In another article, he added the results of histologic studies, revealing the disappearance of amyloid which had been present before. Metraux, 2 in an autopsy of a patient in whom amyloidosis had been temporarily cured clinically, recorded changes in the liver and spleen indicative of the absorption of

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