Abstract

Objective To investigate the anti-inflammatory effect of water-extract of microcos paniculata,and to provide scientific experimental evidence for clinical applications.Methods Various inflammatory models,including the swelling of ear induced by xylene and the permeability increase of capillary induced by acetic acid in mice were used to explore the anti-inflammatory of water-extract of Microcos Paniculata.Results High and middle doses of microcos paniculata could significantly inhibit ear edema,and all the three doses of microcos paniculata could significantly inhibit the permeability increase of capillary permeability.Conclusion The water-extract of microcos paniculata has significant anti-inflammatory effect. Key words: Microeos Paniculata; Water-extract; Anti-inflammatory effect; Ear edema; Capillary permeability

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