Experimental study of the influence of channel length on sclerosing foam stability

Abstract

Objective To understand the influencing factors of foam stability and help reduce the side effects of treatment, and to achieve better therapeutic effect. Methods In the experiment, small diameter rubber tubes of different lengths were used to connect two syringes, and two injectors were injected horizontally to obtain foam and study the effect of channel length on the foam stability. 5ml injector was used, and the ratio of liquid to gas was 1 to 4. Meanwhile, 5 groups of rubber tubes with different lengths were carried out at room temperature. A camera recorded the entire process of foam decay. And foam stability indexes which includes drainage time, half-life, foam half-life volume and the drainage rate curve, were analyzed. Results It showed that when 2cm, 4cm, 6cm and 8cm long rubber tubes were tested, the drainage time of the foam gradually increased from 4s to 27s, while the drainage time of the foam under the 10cm length rubber tube was 18s which was shorter than that of 8cm. Conclusions It shows that the 8 cm length in the experiment is the optimal channel length. The stability of the foam hardener can be improved remarkably by changing the length of the channel, and the foam can be prepared by using a parallel connection device with the best channel length in clinical application. Key words: Channel length; Sclerosing foam preparation method; Foam stability; Venous disease