Abstract

Flow features in branching networks are fundamental for understanding transport processes in respiratory and cardiovascular systems. Specifically for tumor embolization, the ability to predict the fate of finite-size particles in bifurcating vessels is highly desirable for improving embolization efficacy. We use particle tracking velocimetry to investigate the spatial distribution, velocity, acceleration, and dispersion of finite-size particles in a 4-generation bifurcating model. Our results show the remarkable influence of particle concentration on particle transport in several ways, which provides insights relevant to optimizing targeted drug delivery in embolization settings.

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