Experimental study of brachial plexus and vessel compression: evaluation of combined central and peripheral electrodiagnostic approach.

Chaoqun Yang,Jie Chen,Lei Xu,Yu Cao,Jianguang Xu,Yi Zhu,Shulin Li

doi:10.18632/oncotarget.16817

Chaoqun Yang, Jie Chen + Show 5 more

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https://doi.org/10.18632/oncotarget.16817

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Journal: Oncotarget	Publication Date: Apr 4, 2017
Citations: 1	License type: cc-by

Affiliation: Huashan Hospital

Abstract

IntroductionWe sought to investigate the reliability of a new electrodiagnostic method for identifying Electrodiagnosis of Brachial Plexus & Vessel Compression Syndrome (BPVCS) in rats that involves the application of transcranial electrical stimulation motor evoked potentials (TES-MEPs) combined with peripheral nerve stimulation compound muscle action potentials (PNS-CMAPs).ResultsThe latencies of the TES-MEP and PNS-CMAP were initially elongated in the 8-week group. The amplitudes of TES-MEP and PNS-CMAP were initially attenuated in the 16-week group. The isolateral amplitude ratio of the TES-MEP to the PNS-CMAP was apparently decreased, and spontaneous activities emerged at 16 weeks postoperatively.Materials and MethodsSuperior and inferior trunk models of BPVCS were created in 72 male Sprague Dawley (SD) rats that were divided into six experimental groups. The latencies, amplitudes and isolateral amplitude ratios of the TES-MEPs and PNS-CMAPs were recorded at different postoperative intervals.ConclusionsElectrophysiological and histological examinations of the rats’ compressed brachial plexus nerves were utilized to establish preliminary electrodiagnostic criteria for BPVCS.

Highlights

We sought to investigate the reliability of a new electrodiagnostic method for identifying Electrodiagnosis of Brachial Plexus & Vessel Compression Syndrome (BPVCS) in rats that involves the application of transcranial electrical stimulation motor evoked potentials (TES-MEPs) combined with peripheral nerve stimulation compound muscle action potentials (PNS-CMAPs)
The latencies of the TES-MEP and PNS-CMAP were initially elongated in the 8-week group
The amplitudes of TES-MEP and PNS-CMAP were initially attenuated in the 16-week group

Summary

Introduction

We sought to investigate the reliability of a new electrodiagnostic method for identifying Electrodiagnosis of Brachial Plexus & Vessel Compression Syndrome (BPVCS) in rats that involves the application of transcranial electrical stimulation motor evoked potentials (TES-MEPs) combined with peripheral nerve stimulation compound muscle action potentials (PNS-CMAPs). Urschel [1, 2] suggested a representative electrophysiological diagnostic criterion for TOS based on the detection and analysis of the motor nerve conduction velocities of the ulnar nerve at four different points in the upper extremity. Tests of nerve action potentials (NAPs) in the medial antebrachial cutaneous nerve and other sensory tests are highly sensitive methods for the diagnosis of TOS [12, 13]. Confirmatory tests based on imaging techniques, such as magnetic resonance imaging (MRI), may have poor diagnostic specificity due to the anatomical abnormalities associated with TOS that are frequently observed in asymptomatic individuals [14, 15]

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