Abstract
目的 研究自增强型可吸收棒(PDLLA)联合磷酸钙骨水泥(CPC)髓内固定管状骨骨折的可行性,为用于手部掌、指骨骨折提供实验室依据.方法将自增强型可吸收棒植入兔股骨干(横形骨折)髓腔内,两端用磷酸钙骨水泥粘合固定(实验组),克氏针髓内固定(对照组).术后比较两组周围组织的反应,X线片变化及力学强度.结果术后4周实验组和对照组的股骨干横向截骨均未见明显畸形,X线片示实验组的骨痂量多于对照组;测定股骨三点弯曲最大破坏载荷实验,结果两组无明显差异.术后8周剪切力较术后4周无下降.术后8周两组的骨折均愈合,未出现局部反应性肿胀、积液、感染及全身毒性反应.结论自增强型可吸收棒与磷酸钙骨水泥在骨内具有良好的组织相容性,两者联合应用行管状骨骨折髓内固定,效能与克氏针固定相当。
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