Abstract

The feasibility of using vein patch grafts to repair defective tracheal membranous walls was determined. The right jugular veins of 5 adult mongrel dogs were harvested through midline cervical incisions and used as patch grafts. Each cervical trachea was exposed and a full-thickness lesion (2 × 1 cm) was created in the cervical tracheal membranous wall by resecting part of the trachea at the fourth ring below the cricoid cartilage. The defect was repaired by grafting a vein patch to the posterior surface of the injured trachea. All the dogs survived without complications until euthanasia 6 months later. Bronchoscopic examination demonstrated adequate tracheal patency with no inspiratory or expiratory collapse. The constrictive ratio of the cross-sectional area of the most stenotic site to that of the third tracheal ring below the membranous patch was 1.06 ± 0.28. Histologic examination revealed neoepithelium on the surfaces of all the patch grafts. The results indicate that jugular vein patch grafts can be used to repair tracheal membranous wall lesions.

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