Experimental studies on Radioistope Renograms in the Kidney with upper Urinary Tract Obstruction, in parlicular Changes of Segment C

Abstract

The purpose of this report are the comparison of the results between the changes of segment C in RI renogram and of the changes of IVP in various kinds of ureteral obstruction. The results were summarized as follows : 1) The average size of the normal dog kidney and kidney pelvis on x-ray films were; left kidney, 19.2cm2, right kidney, 18.9cm2, left kidney pelvis, 0.9cm2 and right kidney pelvis, 0.3cm2. After the leftside nephrectomy was performed, right kidney became 19.5cm2 and kidney pelvis, 1.98cm2. 2) The changes occurred in obstructed kidney were compared with the types I, II, III, IV, and V of the Fukuchi's classication, types A, B, and C of the Fujino's classificatication and the kidney size of IVP. 3) The height and the time of segments A and B were measured and the height of the curves at 15, 20 and 25 minutes in RI renograms were also measured throughout the experiments. 4) In RI renograms of urinary obstruction, the height of segments A and B increased, that of segment B prolonged and that of segment C disappeared. Finally, segment B disappeared and RI renogram showed nonfunctional type. However, the examination should be done repeatedly to get the final conclusion. 5) The impairment of the renal function differed according to the part of the urinary obstruction. The obstruction in the upper part of the ureter induced impaired renal function constantly, irrespective to the degree of the obstruction. On the other hand, in cases of the lower part obstruction, it appeared more slowly than the former and was parallel to the degree of the obstruction. These results were equally obtained from the RI renogram, IVP and the kidney size estimation. 6) In the teses of hydration, porformed with i. v. injection of 5% glucose solution, the renal function was improved in most cases. 7) The types of RI renogram due to obstruction (segment B elevated continuously for more than 25 minutes) belonged to types III (A, B, C and D) and IV (A, B and D) according to the classification of IVP and were within the limits of 113.2-177.6% as compared with the normal size. Nonfunctional types belonged to the worse one than type V or C. 8) In types II to IV of the Fukuchi's classification, the prolongation and the increasing of the height at 15, 20 and 25 minutes of segment B in renogram were observed and in type V, the height decreased.