EXPERIMENTAL STUDIES ON EXTRACORPOREAL CIRCULATION : ESPECIALLY ON THE BLOOD TRANSFUSION IN DOGS

Abstract

1) Salivery types in 78 mongrel dogs were divided into two groups, namely Otype of 56 dogs (71.8%) and A' type of 22 dogs (28.2%).2) Crossmathches were done in use of dog's plasma, and the agglutinations reacted more strongly than in use of sera. The number of positive reactions was 362 in 1694 trials (21.3%) and was 304 in 847 combination groups (35.8%). Anti Aagglutinin was demonstrated in the plasma of some O'typed dogs.3) Suspension of donor's erythrocytes was injected repeatedly in recipients, and consequently the rise of antibody value was observed in 1 of 7 combination groups. The antibody might be weak anti-A.4) Micrpfilariae were detected in the peripheral blood of dogs in rate of 27.5%.5) Mongrel dogs were divided into 2 groups by the crossmatching and the detection of microfilariae. Crosstransfusion and extracorporeal circulation were done, and the agglutinationreactions and infections of filariae were apparently concerned with bloodtransusionreaction in dogs.6) The bloodtransfusionreaction could be largely prevented by the preliminary examinations of salivery type, crossmatching and detection of microfilare.7) Investigation of the openheart surgery in dogs were indispensable to the progress of clinical heart surgery. Up to the present, the effects of massive bloodtransfusion in dogs were apt to be neglected. Therfore, author tried to investigate the cffects of the massive bloodtransfusion in dogs were apt to be neglected. Therfore, author tried to investigate the the effects of the massive bloodtransfusion and deviced the simplc and effecfive method of their protection.8) The causes of so-ccalled bloodtransfusionreaction in dogs were discussed.