Abstract
After experimental inoculation, severe acute respiratory syndrome coronavirus 2 infection was confirmed in bank voles by seroconversion within 8 days and detection of viral RNA in nasal tissue for up to 21 days. However, transmission to contact animals was not detected. Thus, bank voles are unlikely to establish effective transmission cycles in nature.
Highlights
After experimental inoculation, severe acute respiratory syndrome coronavirus 2 infection was confirmed in bank voles by seroconversion within 8 days and detection of viral RNA in nasal tissue for up to 21 days
All directly inoculated bank voles tested positive for SARS-CoV-2 by quantitative reverse transcription PCR by oral and rhinarium swab specimens at 2 dpi
Two animals were euthanized at 4 dpi; nasal conchae, trachea, lung, and olfactory bulb samples tested positive for SARS-CoV-2 RNA by quantitative reverse transcription PCR (qRT-PCR)
Summary
Severe acute respiratory syndrome coronavirus 2 infection was confirmed in bank voles by seroconversion within 8 days and detection of viral RNA in nasal tissue for up to 21 days. These rodents transmit SARS-CoV-2 to cohoused contact animals and are likely to develop effective infection chains, which could result in independent SARS-CoV-2 transmission cycles in nature and sequential reintroduction to the human population We took swab samples regularly from all animals (Appendix, https://wwwnc.cdc.gov/EID/ article/27/4/20-4945-App1.pdf); we euthanized 1 or Author affiliation: Friedrich-Loeffler-Institut, Greifswald–Insel
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