Abstract

Patients with diffuse small vessel coronary artery disease are often not suitable for direct coronary artery surgery. To gain insight into this problem, the effects on myocardial revascularisation of a free skeletal muscle flap anastomosed to the internal mammary artery were studied in 6 dogs. Four weeks after production of a zone of multiple microinfarctions of the anterior wall of the heart, a free flap of pectoralis muscle was grafted onto the heart. Sixteen to 18 weeks later the animals were sacrificed, and their hearts were subjected to histological and a microvascular corrosion cast examination. The results showed extensive development of a prominent vascular network penetrating from the graft into the heart. Thus, myocardial revascularisation in the dog is possible by grafting a free skeletal muscle onto the heart.

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